MK-0752
Cat. No.：YN380037
CAS No. ：471905-41-6
| 产品名称: | MK-0752 |
| CAS No.: | 471905-41-6 |
| Chemical Name: | cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-cyclohexanepropanoic acid |
| Synonyms: | MK-0752,MK 0752 |
| 分子量: | 442.90 |
| 分子式: | C₂₁H₂₁ClF₂O₄S |
| SMILES: | O=S([C@@]1(C2=C(C=CC(F)=C2)F)CC[C@@H](CCC(O)=O)CC1)(C3=CC=C(Cl)C=C3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MK-0752 是一种高效、口服活性的特异性 γ-分泌酶(γ-secretase)抑制剂，对人 SH-SY5Y 细胞 Aβ40 呈剂量依赖性降低，IC50为 5 nM。MK-0752 穿过血脑屏障。MK-0752 降低体内新生的中枢神经系统 Aβ。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
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