SPL-707
Cat. No.：YN380044
| 产品名称: | SPL-707 |
| CAS No.: | 2195361-33-0 |
| Chemical Name: | |
| Synonyms: | SPL707 |
| 分子量: | 505.54 |
| 分子式: | C₂₇H₂₈FN₅O₄ |
| SMILES: | CC1=C(NC(C[C@@H](C2CC2)C(N[C@@H]3C(N(CC4(CC4)C5)N5C(C6=C3C=CC=C6)=O)=O)=O)=O)C=C(F)C=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SPL-707 是口服有效的，选择性的信号肽肽酶样 2a (SPPL2a) 抑制剂，对 hSPPL2a 的IC50为 77 nM。SPL-707 抑制 γ-分泌酶 (γ-secretase;IC50=6.1 μM) 和SPP(IC50=3.7 μM)。SPL-707 具有靶向 B 细胞和树突状细胞的自身免疫疾病的研究潜力。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
