GSK-3β inhibitor 8
Cat. No.：YN420332
| 产品名称: | GSK-3β inhibitor 8 |
| CAS No.: | 1139875-74-3 |
| Chemical Name: | [2-chloro-4-[[4-(2-thienyl)-2-pyrimidinyl]amino]phenyl](4-methyl-1-piperazinyl)-methanone |
| Synonyms: | |
| 分子量: | 413.9 |
| 分子式: | C20H20ClN5OS |
| SMILES: | CN1CCN(C(C2=C(Cl)C=C(NC3=NC(C4=CC=CS4)=CC=N3)C=C2)=O)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK-3β inhibitor8 是一种噻吩嘧啶衍生物，是有效和选择性的GSK-3β抑制剂 (IC50=64 nM)。GSK-3β inhibitor8 负调控Wnt信号通路，刺激 β 细胞增殖。 |
| IC50和靶点: | [{name:"GSK-3β:64 nM (IC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wang, W., Walker, J.R., Wang, X., et al.Identification of small-molecule inducers of pancreatic β-cell expansionProc. Natl. Acad. Sci. USA106(5),1427-1432(2009)
