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Ganoderic acid DM

Cat. No.:YN420347

  • CAS No. :173075-45-1

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    • 参考文献
    • 产品名称: Ganoderic acid DM
      CAS No.: 173075-45-1
      Chemical Name: 3,7-dioxo-lanosta-8,24E-dien-26-oic acid
      Synonyms:灵芝酸 DM
      分子量:468.66796
      分子式:C30H44O4
      SMILES:C[C@]12C3=C(CC[C@@]1([C@]([C@@H](CC/C=C(C)/C(O)=O)C)([H])CC2)C)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3=O)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ganoderic acid DM 是可从Ganoderma lucidum分离得到的一个天然三萜,可诱导人乳腺癌细胞的 DNA 损伤、G1 细胞周期阻滞和凋亡。Ganoderic acid DM 还是破骨形成的特异性抑制剂。
      IC50和靶点:
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      In Vivo:
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    • Liu, J., Shiono, J., Shimizu, K., et al.Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitorBioorg. Med. Chem. Lett.19(8),2154-2157(2009)

      Wang, K., Bao, L., Xiong, W., et al.Lanostane triterpenes from the Tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and α‑glucosidaseJ. Nat. Prod.78(8),1977-1989(2015)

      Akihisa, T., Nakamura, Y., Tagata, M., et al.Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidumChem. Biodivers.4(2),224-231(2007)

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