Ganoderic acid DM
Cat. No.:YN420347
产品名称: | Ganoderic acid DM |
CAS No.: | 173075-45-1 |
Chemical Name: | 3,7-dioxo-lanosta-8,24E-dien-26-oic acid |
Synonyms: | 灵芝酸 DM |
分子量: | 468.66796 |
分子式: | C30H44O4 |
SMILES: | C[C@]12C3=C(CC[C@@]1([C@]([C@@H](CC/C=C(C)/C(O)=O)C)([H])CC2)C)[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC3=O)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ganoderic acid DM 是可从Ganoderma lucidum分离得到的一个天然三萜,可诱导人乳腺癌细胞的 DNA 损伤、G1 细胞周期阻滞和凋亡。Ganoderic acid DM 还是破骨形成的特异性抑制剂。 |
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Liu, J., Shiono, J., Shimizu, K., et al.Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitorBioorg. Med. Chem. Lett.19(8),2154-2157(2009)
Wang, K., Bao, L., Xiong, W., et al.Lanostane triterpenes from the Tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and α‑glucosidaseJ. Nat. Prod.78(8),1977-1989(2015)
Akihisa, T., Nakamura, Y., Tagata, M., et al.Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidumChem. Biodivers.4(2),224-231(2007)