PF-04802367
Cat. No.：YN420350
CAS No. ：1962178-27-3
| 产品名称: | PF-04802367 |
| CAS No.: | 1962178-27-3 |
| Chemical Name: | |
| Synonyms: | PF-367 |
| 分子量: | 361.78 |
| 分子式: | C16H16ClN5O3 |
| SMILES: | COC1=C(Cl)C=C(C=C1)C2=C(N=CO2)C(=O)NCCC[N]3C=NC=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-04802367 (PF-367) 是一种高选择性GSK-3抑制剂，对GSK-3β酶的IC50为 2.1 nM。PF-04802367 具有理想的中枢神经系统 (CNS) 特性和效力。PF-04802367 抑制两种GSK-3亚型（GSK-3α和GSK-3β）效果差不多，IC50值分别为 10.0 和 9.0 nM。 |
| IC50和靶点: | [{name:"GSK-3α:10 nM (IC50)"},{name: "GSK-3β:9 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
