GSK3β inhibitor II
Cat. No.：YN420359
CAS No. ：478482-75-6
| 产品名称: | GSK3β inhibitor II |
| CAS No.: | 478482-75-6 |
| Chemical Name: | 4-[5-[[(3-iodophenyl)methyl]thio]-1,3,4-oxadiazol-2-yl]-pyridine |
| Synonyms: | |
| 分子量: | 395.2 |
| 分子式: | C14H10IN3OS |
| SMILES: | IC1=CC(CSC2=NN=C(C3=CC=NC=C3)O2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK3β inhibitor II 是GSK3β的抑制剂。GSK3β inhibitor II 可用于阿尔茨海默病 (AD) 的研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Naerum, L., Nørskov-Lauritsen, L., and Olesen, P.H.Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitorsBioorg. Med. Chem. Lett.12(11),1525-1528(2002)
Watcharasit, P., Bijur, G.N., Song, L., et al.Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53J. Biol. Chem.278(49),49972-48879(2003)
Lahmy, V., Meunier, J., Malström, S., et al.Blockade of Tau hyperphosphorylation and Aβ1-42 generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ1 receptor agonist, in a nontransgenic mouse model of Alzheimer's diseaseNeuropsychopharmacology38(9),17061723(2013)
