SN32976
Cat. No.：YN420385
| 产品名称: | SN32976 |
| CAS No.: | 1246202-11-8 |
| Chemical Name: | |
| Synonyms: | SN 32976;SN32976 |
| 分子量: | 581.64 |
| 分子式: | C24H33F2N9O4S |
| SMILES: | C(N(C)C)CS(N1CCN(C2=NC(N3C4=CC=CC(OC)=C4N=C3C(F)F)=NC(N3CCOCC3)=N2)CC1)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SN32976 是一种有效的选择性 I 类PI3K和mTOR抑制剂，对PI3Kα、PI3Kβ、PI3Kγ、PI3Kδ和mTOR的IC50值分别为 15.1 nM、461 nM、110 nM、134 nM 和 194 nM。SN32976 在其他 442 种激酶中表现出高选择性。SN32976 具有抗癌活性。 |
| IC50和靶点: | [{name:"PI3Kα:15.1 nM (IC50)"},{name: "PI3Kβ:461 nM (IC50)"},{name: "PI3Kγ:110 nM (IC50)"},{name: "PI3Kδ:134 nM (IC50)"},{name: "mTOR:194 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
