(Rac)-BRD0705
Cat. No.:YN420390
产品名称: | (Rac)-BRD0705 |
CAS No.: | 1597440-03-3 |
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分子量: | 321.42 |
分子式: | C20H23N3O |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (Rac)-BRD0705 是 BRD0705 的低活性外消旋体,BRD0705 是一种有效的,具有旁系选择性和口服活性的 GSK3α 抑制剂,IC50为 66 nM,Kd为 4.8 μM。BRD0705 与 GSK3β (IC50为 515 nM) 相比,对 GSK3α 的选择性更高 (8 倍)。BRD0705 可用于急性髓细胞性白血病。 |
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