Artemisinin
Cat. No.：YN420282
CAS No. ：63968-64-9
规格
价格(RMB)
库存
| 产品名称: | Artemisinin |
| CAS No.: | 63968-64-9 |
| Chemical Name: | (3R,5aS,6R,8aS,9R,12S,12aR)-octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one |
| Synonyms: | 青蒿素; Qinghaosu; NSC 369397 |
| 分子量: | 282.33 |
| 分子式: | C₁₅H₂₂O₅ |
| SMILES: | O=C1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，从青蒿 (Artemisia annuaL.) 植物的地上部分分离的抗疟疾药物。Artemisinin 以剂量依赖性方式降低pAKT来抑制 AKT 信号通路。Artemisinin 可减少癌细胞的增殖，迁移，侵袭，肿瘤发生和转移，同时 Artemisinin 有神经保护作用。 |
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Akoachere, M., Buchholz, K., Fischer, E., et al.In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisininsAntimicrob. Agents Chemother.49(11),4592-4597(2005)
Zhu, S., Liu, W., Ke, X., et al.Artemisinin reduces cell proliferation and induces apoptosis in neuroblastomaOncol. Rep.32(3),1094-1100(2014)
Ooko, E., Saeed, M.E.M., Kadioglu, O., et al.Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cellsPhytomedicine22(11),1045-1054(2015)
Robert, A., Benoit-Vical, F., Claparols, C., et al.The antimalarial drug artemisinin alkylates heme in infected miceProc. Natl. Acad. Sci. USA102(38),13676-13680(2005)
Chawira, A.N., Warhurst, D.C., Robinson, B.L., et al.The effect of combinations of qinghaosu (artemisinin) with standard antimalarial drugs in the suppressive treatment of malaria in miceTrans. R. Soc. Trop. Med. Hyg.81(4),554-558(1987)
