Esculetin
Cat. No.：YN420294
CAS No. ：305-01-1
规格
价格(RMB)
库存
| 产品名称: | Esculetin |
| CAS No.: | 305-01-1 |
| Chemical Name: | 6,7-dihydroxy-2H-1-benzopyran-2-one |
| Synonyms: | 秦皮乙素 |
| 分子量: | 178.14 |
| 分子式: | C₉H₆O₄ |
| SMILES: | O=C1C=CC2=CC(O)=C(O)C=C2O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Esculetin 是一种主要从水曲柳 (Fraxinus rhynchophylla) 的树皮中提取的活性成分。 Esculetin 通过抑制PI3K/Akt途径来抑制血小板衍生生长因子 (PDGF) 诱导的气道平滑肌细胞 (ASMCs) 表型转换。Esculetin 具有抗氧化，抗炎和抗肿瘤的作用。 |
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Neichi, T., Koshihara, Y., and Murota, S.I.Inhibitory effect of esculetin on 5-lipoxygenase and leukotriene biosynthesisBiochim. Biophys. Acta753,130-132(1983)
Sayegh, J., Cao, J., Zou, M.R., et al.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screenJ. Biol. Chem.288(13),9408-9417(2013)
Jurd, L., Corse, J., King, A.D., Jr., et al.Antimicrobial properties of 6,7-dihydroxy-, 7,8-dihydroxy-, 6-hydroxy- and 8-hydroxycoumarinsPhytochem.10(12),2971-2974(1971)
Angeles, D.C., Ho, P., Dymock, B.W., et al.Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2Ann. Clin. Transl. Neurol.3(4),288-294(2016)
Tubaro, A., Del Negro, P., Ragazzi, E., et al.Anti-inflammatory and peripheral analgesic activity of esculetin in vivoPharmacol. Res. Commun.20(5),83-85(1988)
