Nepodin
Cat. No.：YN420309
CAS No. ：3785-24-8
规格
价格(RMB)
库存
| 产品名称: | Nepodin |
| CAS No.: | 3785-24-8 |
| Chemical Name: | 1-(1,8-dihydroxy-3-methyl-2-naphthalenyl)-ethanone |
| Synonyms: | Musizin |
| 分子量: | 216.23 |
| 分子式: | C₁₃H₁₂O₃ |
| SMILES: | CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nepodin (Musizin) 是一种醌氧化还原酶 (PfNDH2) 抑制剂，从Rumex crispus中分离。Nepodin (Musizin) 通过激活 AMPK 刺激 GLUT4 向质膜的转运。Nepodin (Musizin) 具有抗糖尿病和抗疟疾的作用。 |
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Grover, J., Kumar, V., Singh, V., et al.Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitorsEur. J. Med. Chem.80,47-56(2014)
Lee, J.H., Kim, Y.G., Khadke, S.K., et al.Inhibition of biofilm formation by Candida albicans and polymicrobial microorganisms by nepodin via hyphal-growth suppressionACS Infect. Dis.5(7),1177-1187(2019)
Lee, K.H., and Rhee, K.H.Antimalarial activity of nepodin isolated from Rumex crispusArch. Pharm. Res.36(4),430-435(2013)
Ha, B.G., Yonezawa, T., Son, M.J., et al.Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivoBiofactors40(4),436-447(2014)
