3,3'-Diindolylmethane
Cat. No.：YN481468
| 产品名称: | 3,3'-Diindolylmethane |
| CAS No.: | 1968-05-4 |
| Chemical Name: | 3,3'-methylenebis-1H-indole |
| Synonyms: | DIM; Arundine; HB 236 |
| 分子量: | 246.31 |
| 分子式: | C₁₇H₁₄N₂ |
| SMILES: | C1(CC2=CNC3=C2C=CC=C3)=CNC4=C1C=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3，3'-Diindolylmethane 是一种有效的雄激素受体 (AR) 拮抗剂。 |
| IC50和靶点: | |
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Wong, C.P., Hsu, A., Buchanan, A., et al.Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cellsPLoS One9(1),(2014)
Wu, T.Y., Khor, T.O., Su, Z.Y., et al.Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumorsAAPS J.15(3),864-874(2013)
Xu, Y., Zhang, J., Shi, W., et al.Anticancer effects of 3,3'-diindolylmethane are associated with G1 arrest and mitochondria-dependent apoptosis in human nasopharyngeal carcinoma cellsOncol. Lett.5(2),655-662(2013)
Fan, S., Meng, Q., Xu, J., et al.DIM (3,3'-diindolylmethane) confers protection against ionizing radiation by a unique mechanismProc. Natl. Acad. Sci. USA110(46),18650-18655(2013)
