RU 58841
Cat. No.:YN480279
产品名称: | RU 58841 |
CAS No.: | 154992-24-2 |
Chemical Name: | 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)-benzonitrile |
Synonyms: | PSK-3841; HMR-3841 |
分子量: | 369.34 |
分子式: | C₁₇H₁₈F₃N₃O₃ |
SMILES: | FC(F)(C1=C(C=CC(N2C(C(C)(N(C2=O)CCCCO)C)=O)=C1)C#N)F |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RU 58841 (PSK-3841) 是雄激素受体拮抗剂,可促进头发再生。 |
IC50和靶点: | |
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Battmann, T., Bonfils, A., Branche, C., et al.RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutismJ. Steroid Biochem. Mol. Biol.48(1),55-60(1994)
Obana, N., Chang, C., and Uno, H.Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaqueEndocrinology138(1),356-361(1997)