S-23
Cat. No.：YN480528
CAS No. ：1010396-29-8
规格
价格(RMB)
库存
| 产品名称: | S-23 |
| CAS No.: | 1010396-29-8 |
| Chemical Name: | (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-propanamide |
| Synonyms: | S23,(S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide |
| 分子量: | 416.75 |
| 分子式: | C₁₈H₁₃ClF₄N₂O₃ |
| SMILES: | O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)[C@@](C)(O)COC2=CC=C(Cl)C(F)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | S-23 是一种口服选择性雄激素受体调节剂(SARM)，Ki为 1.7 nM。S-23 诱导 CV-1 细胞雄激素受体介导的转录激活。S-23 增加去势大鼠前列腺、精囊和肛提肌重量。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jones, A., Chen, J., Hwang, D.J., et al.Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: A selective androgen receptor modulator for hormonal male contraceptionEndocrinology150(1),385-395(2009)
Jones, A., Hwang, D.J., Duke, C.B., III, et al.Nonsteroidal selective androgen receptor modulators enhance female sexual motivationJ. Pharmacol. Exp. Ther.334(2),439-448(2010)
