Cyproterone acetate
Cat. No.：YN481258
CAS No. ：427-51-0
规格
价格(RMB)
库存
| 产品名称: | Cyproterone acetate |
| CAS No.: | 427-51-0 |
| Chemical Name: | (1β,2β)-17-acetyloxy-6-chloro-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione |
| Synonyms: | 醋酸环丙孕酮 |
| 分子量: | 402.91 |
| 分子式: | C₂₃H₂₇ClO₄ |
| SMILES: | C[C@@]12C(C(Cl)=C[C@]3([H])[C@]2([H])C[C@@]4(C)[C@@]3([H])CC[C@@]4(C(C)=O)OC(C)=O)=CC([C@H]5[C@@H]1C5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cyproterone acetate 是一种抗雄激素 (IC50=7.1 nM) 和孕激素合成的类固醇。Cyproterone acetate 与 progesteron 和糖皮质激素受体有亲和力。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hamann, L.G., Higuchi, R.I., Zhi, L., et al.Synthesis and biological activity of a novel series of nonsteroidal, peripherally selective androgen receptor antagonists derived from 1,2-dihydropyridono[5,6-g]quinolinesJ. Med. Chem.41(4),623-639(1998)
Steinbeck, H., Mehring, M., and Neumann, F.Comparison of the effects of cyproterone, cyproterone acetate and oestradiol on testicular function, accessory sexual glands and fertility in a long-term study on ratsJ. Reprod. Fertil.26(1),65-76(1971)
Kasper, P., and Mueller, L.Sex-specific induction of apoptosis by cyproterone acetate in primary rat hepatocytesCarcinogenesis20(11),2185-2188(1999)
