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Nilutamide

Cat. No.:YN481343

  • CAS No. :63612-50-0

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    • 产品名称: Nilutamide
      CAS No.: 63612-50-0
      Chemical Name: 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione
      Synonyms:Nilandron; RU 23908
      分子量:317.22
      分子式:C₁₂H₁₀F₃N₃O₄
      SMILES:O=C1N(C2=CC=C([N+]([O-])=O)C(C(F)(F)F)=C2)C(C(C)(C)N1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Nilutamide (Nilandron) 是一种有潜力用于转移性前列腺癌的非甾体抗雄激素药物。
      IC50和靶点:
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      Solvent & Solubility:
    • Signh, S.M., Gauthier, S., and Labrie, F.Androgen receptor antagonists (antiandrogens): Structure-activity relationshipsCurr. Med. Chem.7(2),211-247(2000)

      Simard, J., Singh, S.M., and Labrie, F.Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parametersUrology49(4),580-586(1997)

      Wakeling, A.E., Furr, B.J.A., Glen, A.T., et al.Receptor binding and biological activity of steroidal and nonsteroidal antiandrogensJ. Steroid Biochem.15,355-359(1981)

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