Nilutamide
Cat. No.:YN481343
产品名称: | Nilutamide |
CAS No.: | 63612-50-0 |
Chemical Name: | 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione |
Synonyms: | Nilandron; RU 23908 |
分子量: | 317.22 |
分子式: | C₁₂H₁₀F₃N₃O₄ |
SMILES: | O=C1N(C2=CC=C([N+]([O-])=O)C(C(F)(F)F)=C2)C(C(C)(C)N1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Nilutamide (Nilandron) 是一种有潜力用于转移性前列腺癌的非甾体抗雄激素药物。 |
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Signh, S.M., Gauthier, S., and Labrie, F.Androgen receptor antagonists (antiandrogens): Structure-activity relationshipsCurr. Med. Chem.7(2),211-247(2000)
Simard, J., Singh, S.M., and Labrie, F.Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parametersUrology49(4),580-586(1997)
Wakeling, A.E., Furr, B.J.A., Glen, A.T., et al.Receptor binding and biological activity of steroidal and nonsteroidal antiandrogensJ. Steroid Biochem.15,355-359(1981)