Darolutamide
Cat. No.：YN481574
CAS No. ：1297538-32-9
规格
价格(RMB)
库存
| 产品名称: | Darolutamide |
| CAS No.: | 1297538-32-9 |
| Chemical Name: | N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide |
| Synonyms: | ODM-201; BAY-1841788 |
| 分子量: | 398.85 |
| 分子式: | C₁₉H₁₉ClN₆O₂ |
| SMILES: | ClC1=C(C#N)C=CC(C2=NN(C[C@H](C)NC(C3=NNC(C(O)C)=C3)=O)C=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Darolutamide (ODM-201;BAY-1841788) 是有效的雄激素受体 (AR) 拮抗剂, 在体内试验中的IC50值为26 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Moilanen, A.M., Riikonen, R., Oksala, R., et al.Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapiesSci. Rep.5:12007,(2015)
