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Danazol

Cat. No.:YN481938

  • CAS No. :17230-88-5

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    • 产品名称: Danazol
      CAS No.: 17230-88-5
      Chemical Name: pregna-2,4-dien-20-yno[2,3-d]isoxazol-17α-ol
      Synonyms:达那唑
      分子量:337.46
      分子式:C₂₂H₂₇NO₂
      SMILES:C#C[C@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC5=C(C=NO5)C[C@]4(C)[C@@]3([H])CC[C@@]21C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Danazol是合成类固醇Ethisterone的衍生物, 抑制促性腺激素产生, 且具有一定的弱雄激素作用。
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    • Ma, R., Cotton, B., Lichtensteiger, W., et al.UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assayToxicol. Sci.74(1),43-50(2003)

      Cottreau, C.M., Ness, R.B., Modugno, F., et al.Endometriosis and its treatment with danazol or lupron in relation to ovarian cancerClin. Cancer Res.9(14),5142-5144(2003)

      Haning, R.V., Jr., Carlson, I.H., Cortes, J., et al.Danazol and its principal metabolites interfere with binding of testosterone, cortisol, and thyroxin by plasma proteinsClin. Chem.28(4 Pt 1),696-698(1982)

      Peters, T.G., Lewis, J.D., Wilkinson, E.J., et al.Danazol therapy in hormone-sensitive mammary carcinomaCancer40(6),2797-2800(1977)

      Benz, C., Hollander, C., and Miller, B.Endocrine-responsive pancreatic carcinoma: Steroid binding and cytotoxicity studies in human tumor cell linesCancer Res.46(5),2276-2281(1986)

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